Explanation: In the process of skull repair surgery, a very important point is how to choose the materials used for skull repair. Because the repair material is often accompanied by the patient’s life for many years, so the choice of material first requires a high degree of biocompatibility, and need to ensure a certain degree of strength and stiffness, not only to provide strong enough to protect, but also to meet the needs of intraoperative molding, to achieve the appearance of the repair of cosmetic surgery to achieve the satisfactory results. So what are the main materials used in cranial bone repair? Answer: Now we have decades of development of cranial bone repair surgery, but also gradually updated, as early as 20 years ago, when we first went to work with plexiglass, or even cementless. Through the evolution of materials, in terms of the last 20 years, titanium mesh has become a major repair material. As you can see, this is the titanium alloy material that we use, whether we call it titanium plate, whether we call it titanium mesh, it’s all these kinds of things that cover the area of the skull defect. Another material that we have developed in recent years is PEEK, which is called polyether ether ketone, and this is a material that we have used in recent years for cranial bone repair, which can replace the titanium mesh. You can see that titanium mesh is relatively soft, you can take a look at this, although it is a metal material, but made very thin, so that when we press, it has a certain deformation, PEEK material is relatively speaking very good hardness, and preoperative design when we are also three-dimensional design, completely fit to the area of the cranial defect, and then fixed to form a perfect repair, this is the current use of these two materials. These are the two materials currently used. These two materials are in line with the human body, tissue compatibility is very good material. Explanation: As two commonly used materials in cranial bone repair surgery, what are the characteristics of titanium alloy and PEEK? What are the differences between them? Answer: 20 years ago we began to use titanium mesh materials for skull repair, then also very advanced materials, tissue compatibility is very good, very few phenomena of rejection. It has been used for more than 20 years and is a very mature material. But after all, it is a metal, it is a conductor of heat and cold, in which case some people are more sensitive, including the southern region of excessive heat, as well as the northern region of excessive cold, some people will have localized discomfort (using) titanium mesh, it has a certain feeling, such as exposure to the sun or the cold area, the local feeling of too cold and too hot, which is indeed the case. Another is that titanium mesh strength is not so strong, is the clinical encountered a few cases, such as impact, titanium mesh caused by localized depression. PEEK material is also a new material in the last decade, the earliest PEEK material is used in orthopedic spine surgery to replace the artificial disc of a material, of course, this material is more expensive, with orthopedic volume is relatively small, in recent years because of the progress of the materials used in neurosurgery of this region. The strength of this material is very strong, we have done impact experiments, the strength is close to, or even stronger than the strength of the skull, the ability to resist blows is very good. So this material now has the trend of gradually replacing titanium mesh.