The advanced functions of insulin pumps generally include several aspects: the use of adjustments to insulin basal and high-dose modes, the application of carbohydrate coefficients to achieve the function of how much to eat and how much to hit, and the application of the concept of correcting high doses to achieve just the right amount of correction when blood glucose is too high or too low [5]. These functions are actually realized by changing the electronic chip program of the human-machine dialogue, avoiding the tedious calculation process and memory errors of the pump wearer, thus realizing convenient and fast adjustment, so called smart guider. For pump wearers, being able to use the advanced functions of insulin pump means that you have learned how to self-regulate blood glucose, and the life of diabetic patients is thus moving towards a life with smooth blood glucose control and quality. The subcutaneous injection mode of action of insulin, the selection of the right person to wear the pump, and the full cooperation between medical and nursing care are impossible to achieve, which is an important reason why the author has taken great pains to introduce its background knowledge earlier. The following specifies how to apply these advanced features. Insulin pump basal rate mode flexible application involves two aspects: First, according to the specific life and work mode to choose a different basal rate mode, such as holidays love to sleep and usually work in the morning basal rate mode can be set to two modes to switch freely, fixed time exercise patients can set a specific day basal rate mode, many advanced pumps can now store at least two basal rate mode. The second is the application of temporary basal rate, temporary basal rate is suitable for temporary adjustment of basal rate for specific occasions, such as fever and fasting phase. High-dose mode can be divided into normal mode, square-wave mode and double-wave mode. Normal mode means that high-dose insulin is injected within a few minutes at once, square-wave mode means that high-dose insulin is injected evenly over a long period of time, and double-wave mode means that high-dose insulin is proportionally divided into normal mode at the front and square-wave mode at the back. For example, carbohydrate-based insulin is suitable for normal mode, fatty meal or high-protein meal is suitable for square wave mode, and if the meal time is long, square wave or double wave mode is suitable. In the high dose wizard, a carbohydrate factor (carb factor) should be set to solve the problem of how many carbohydrates to eat and how much insulin to take. The carbohydrate factor can be calculated by the 500 rule, i.e. 500 divided by the total insulin requirement, and can be further adjusted by testing the carbohydrate factor during the fine tuning phase. There is a correct bolus in the high dose wizard, which is to solve the problem of how much more or less insulin is needed to bring blood glucose down to the target blood glucose within 3-4 hours when blood glucose is too high or too low. The insulin sensitivity factor (correction factor) and active insulin (also called bolus on board) concepts, insulin sensitivity factor is equivalent to how many millimoles per liter of blood glucose can be lowered by 1 unit of insulin, and the insulin sensitivity factor can be calculated by the 110 rule, i.e. 110 divided by the total subcutaneous dose of insulin in a day ( TDD). Active insulin refers to the insulin that can lower blood glucose after a period of subcutaneous insulin injection, and this concept emphasizes the ability of insulin to continue to lower blood glucose, that is, its activity. The duration of action of rapid-acting insulin is generally set at 3 hours, while the duration of action of short-acting insulin is generally set at 4 hours, and the same dose of rapid-acting insulin has a strong hypoglycemic effect within one hour, but its maintenance time is short; the larger the dose, the longer the duration of action of insulin, for example, for a 50 kg weight patient at 0.075 U/kg compared with 0.3 U/kg, the active duration of action of 3.75 U of insulin can only The concept of active insulin is a common problem that doctors tend to ignore at present, and we often encounter some problems of overkill of hyperglycemia in clinical practice, and one important reason is that the concept of active insulin in large residual doses is not considered. To give an example for better impression, a patient with type 1 diabetes has a total subcutaneous insulin dose of 40U a day, and his insulin sensitivity coefficient is 110/40=2.75, his blood glucose is 15mM 2h after breakfast, his target blood glucose is 7.8mM 2 hours after meal, and he injects 10U of short-acting insulin before meal, and asks whether he needs to add how many units of insulin subcutaneously. Based on the insulin sensitivity coefficient, it can be calculated that the additional dose needed is (15-7.8)/2.75=2.61U of insulin, but if we consider that the residual insulin amount is 5 U (according to the insulin activity time is 4 hours, the insulin effect is evenly distributed in 4 hours), there is no need for additional dose. In fact, this patient’s pre-lunch blood glucose is 6mM without additional insulin. If the large dose is corrected in one day If the corrected high dose exceeds 8% of the total dose in a day, it indicates that the high dose or basal rate setting is not reasonable and needs to be readjusted. At present, many pumps have set this function to correct the high dose, which can automatically calculate the amount of residual active insulin from previous injections and integrate it into the next postprandial high dose, which can effectively solve the problem of overcorrecting the blood glucose afterwards. The second best way is to not overtreat it. “The concept of carbohydrate factor of high dose wizard, the flexible application of basal rate and high dose pattern is the first half of this quote, and the concept of correcting high dose is the second half of this quote.