Creatinine 110.8μmol/L need to improve the relevant examination, clarify the cause of the disease, for the cause of the treatment. Normal male serum creatinine is between 53~106μmoI/L, female is between 44~97μmoI/L. Creatinine 110.8μmol/L belongs to mild elevation, which may be caused by acute kidney injury, chronic renal insufficiency, or physiological factors such as eating more meat and exercising more. If it is acute kidney injury, it needs to be treated according to the cause. For example, drug-induced acute kidney injury needs to stop using the relevant drugs, infections caused by the need to apply antibiotics and other drugs for treatment, blood loss caused by insufficient renal blood flow needs to be rehydrated and other related treatments. In case of chronic renal insufficiency, patients can apply ACEI or ARB drugs such as captopril and valsartan to lower blood pressure, reduce urinary protein, slow down the progression of renal function and other related treatments. Hormones or other immunosuppressants such as methylprednisolone and cyclophosphamide can be applied when necessary. If the blood creatinine is elevated due to physiological factors such as eating more meat and exercising more, the blood creatinine will be reduced to normal level after avoiding the influencing factors. All of the above medications should be used under the guidance of a doctor, avoid self-medication. If the patient found that the blood creatinine increased, it is recommended to go to the regular hospital in time, complete the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.