Symptoms of stomach discomfort in the morning on an empty stomach are mainly considered to be caused by gastric diseases, such as Helicobacter pylori infection, erosive gastritis, cardia cancer of the fundus of the stomach and so on, because inflammation or occupying lesions occurring in the stomach will lead to congestion, ulceration, erosion and other phenomena of the muscular layer of the stomach wall tissues. In the morning, the human stomach is relatively in the fasting state, and the increased concentration of gastric acid will aggravate the stimulating effect on the lesion tissue, thus aggravating the adverse symptoms such as gastric distension and pain, nausea, vomiting, acid reflux and burning, etc. The patient may not be excluded from having duodenal cardia cancer. However, it is not excluded that patients have duodenal bulb ulcer, acute inflammatory splenomegaly, pancreatic ductal cell carcinoma and other digestive diseases, because the above organs and tissues have close relationship with the stomach, and once it occurs organic lesions, it will form continuous pressure and stimulation to the outer mucous membrane of the stomach, and cause patients to bleed with gastric discomfort symptoms.