I. What is epilepsy? What is migraine? Epilepsy is a group of clinical syndromes of chronic brain dysfunction caused by a variety of causes, and is a seizure, sudden, recurrent, transient disorder of the brain nervous system caused by repeated discharges of neurons in the brain. Migraine is a recurrent throbbing headache, which is one of the most common types of headaches. It can be accompanied by neurological and mental dysfunction before or during the onset of headache. It is also a progressively worsening disease, usually with increasing frequency. The main points of differentiation between migraine and epilepsy: 1. Migraine mostly has a positive family history of the disease, while epilepsy generally does not have a positive family history of migraine. 2. Headache epilepsy has an acute onset, mostly temporal and frontal, often bilateral, and is accompanied by other autonomic symptoms. Migraine occurs relatively slowly, mostly with triggering factors, and typically with pulsating throbbing on one side after the aura. 3. The EEG is paroxysmal spike waves or spike-slow complex waves, while the EEG of intermittent migraine may have focal slow waves and mesial temporal spike waves, but they appear on the ipsilateral side of the headache and often disappear after falling asleep. This is different from the typical spike waves of epilepsy and appear on the contralateral side of the headache. Migraine has no change in the EEG or shows a slowed background wave rhythm during the seizure, whereas epilepsy has significant epileptiform discharges. 4. The disturbance of consciousness in epilepsy occurs suddenly, terminates quickly, and is severe, whereas the disturbance of consciousness in basilar artery migraine occurs slowly and is easily aroused. 5.Trial treatment: Some patients do have difficulty in identification and can be treated with a trial of anti-migraine drugs. The above is the difference between seizures and migraine. Migraine can be complicated by clinical seizures, and the two often appear in the form of cross-over, but the diagnosis of “headache epilepsy” cannot be made by EEG abnormalities alone.