Thyroid stimulating hormone 7.21μIU/ml, has exceeded the normal range, if FT4, FT3 is normal, then it may not be serious, but if FT4, FT3 is reduced, it can be considered primary hypothyroidism, whether it is serious or not needs to be combined with clinical symptoms and other conditions to determine the overall situation, it is recommended to consult a doctor. 1. If there is only 7.21μIU/ml of thyrotropin and normal FT4 and FT3, subclinical hypothyroidism can be considered clinically, which is usually not serious and does not require drug treatment. If the patient is accompanied by symptoms of hypothyroidism, positive TPOAb, dyslipidemia, or atherosclerotic disease, thyroid hormone treatment should be given. 2. If the thyrotropin is 7.21μIU/ml, combined with the decrease of FT4 and FT3, the clinical diagnosis of hypothyroidism can be considered, and then it is necessary to take levothyroxine under the guidance of professional endocrinologists. It is recommended that patients with elevated thyroid-stimulating hormone should seek prompt medical attention.