Patients with Hashimoto’s thyroiditis usually show only positive thyroid peroxidase antibodies in the early stages of the disease and have no clinical symptoms. In the later stages of the disease, symptoms of hypothyroidism, such as chills and fatigue, may appear. In most cases, patients with Hashimoto’s thyroiditis first present with goiter or hypothyroidism. The disease may present as a moderately enlarged thyroid gland with a firm texture. When hypothyroidism is present, patients may present with symptoms such as chills, fatigue, a feeling of swelling in the hands and feet, drowsiness, memory loss, less sweating, joint pain, weight gain, constipation, menstrual disorders in women, or excessive menstruation, and infertility. Patients with Hashimoto’s thyroiditis need to seek medical attention in a timely manner and be treated under the guidance of a doctor.