Dapoxetine Hydrochloride Tablets not responding after 2 hours may be due to insufficient dosage, not swallowing the whole tablet, taking it for too short a period of time or exceeding the time and so on. 1. Insufficient dosage: the minimum dosage may not be reached, or the low dosage does not work, you can increase the dosage appropriately under the guidance of the doctor. 2. Not swallowing the whole tablet: chewing or breaking the tablet will affect the effect of the medicine. The tablets should be swallowed whole and patients are advised to take the medication with at least a full glass of water. 3. Taking time is too short or more than time: Dapoxetine hydrochloride tablets need to be taken about 1~3 hours before sex, if too early the effect of the drug has not been played, too late the effect of the drug has been played, will lead to ineffective. Dapoxetine Hydrochloride Tablets are intended for the treatment of men between the ages of 18 and 64 who suffer from premature ejaculation. The use of dapoxetine hydrochloride can cause adverse reactions such as headache, dizziness, nausea, and diarrhea. The drug is contraindicated in people with a known allergy to the product, in patients with a significant pathological condition of the heart, in patients with moderate and severe liver damage. The drug should also not be used in conjunction with thioridazine, strong cytochrome P450 3A4 inhibitors, and monoamine oxidase inhibitors. Dapoxetine Hydrochloride Tablets are prescription medications and should be used under the supervision of a physician if needed to minimize the risk of medication.