Clinically, the area between the upper and lower articular processes of the human lumbar arch is referred to as the isthmus. If congenital developmental malformation, traumatic fracture, chronic injury, etc., resulting in the lumbar vertebrae on one or both sides of the arch or inter-isthmus bone continuity interruption, it is called isthmic discontinuity or vertebral disintegration, on the basis of isthmic discontinuity, once by external force, the diseased vertebrae together with the above lumbar vertebrae slide forward, it is called lumbar spine slippage, slippage phenomenon to 20 to 50 years old age group for more. The main manifestation of slippage is: long-term recurrent lower back pain, sometimes pain can be radiated to the sacroiliac area and lower limbs, in standing, walking, bending and weight-bearing, pain aggravated, while bed rest, can reduce the symptoms. In a very small number of severe patients, there may also be strain and compression of the cauda equina nerve and weakness of the lower extremities, urinary and bowel dysfunction and even incomplete paralysis. If only the isthmus disintegrates without slippage, it is sometimes asymptomatic. The lower back pain is milder and the patient can perform general labor. The extent of the disease often depends on the type of isthmus discontinuity, the spinal instability and the severity of the slippage and the age of the patient. For lumbar spondylolisthesis, a clear diagnosis can be made by x-ray and MR examination, and the degree of spondylolisthesis, nerve compression and the presence of combined disc herniation can also be distinguished. Conservative treatment is suitable for those who have simple collapse, no obvious slippage and mild clinical symptoms. The main measures include: (1), lumbar back muscle exercise, which is especially important to increase the lumbar spine’s monthly acute characterization. (2), lumbar brace method. (3), avoid lumbar trauma, heavy load and strenuous exercise. (4), symptomatic treatment. Lumbar physical therapy, massage and medication may be implemented. Note: Do not push and hold. If the conservative treatment is effective, then the lumbar back muscle exercise must be strengthened, otherwise, it is easy to recur or reappear slippage. 2, surgery for conservative treatment is ineffective, the symptoms of recurrence, then often need surgery, surgery can have serious compression of the nerve root, give decompression and vertebral body reset, internal fixation and fusion.