The cause of gallstone pain may be caused by biliary colic, or it may be caused by inflammation of the gallbladder. Biliary colic is mainly refers to the gallbladder stone in the bile duct opening embedded, such as in the jugular abdomen embedded and lead to the gallbladder inside the bile discharge is not smooth, the patient has a biliary colic symptoms attack, the pain is very obvious, the main location is in the epigastric as well as the subglottic area, but also in the right epigastric pain, at the same time, it may be accompanied by back pain, and the right shoulder pain, etc., the patient pain is intolerable, and sometimes flexion to try to ease the pain. The patient is in pain, sometimes in a flexed position in an attempt to relieve the pain. The patient’s gallbladder is infected by bacteria leading to inflammation of the gallbladder causing pain, such as chronic cholecystitis, acute cholecystitis, chronic cholecystitis patients with pain is relatively mild, sometimes hidden pain, swelling. If acute cholecystitis, the patient’s pain is more obvious, usually in the right upper abdomen predominantly, there may be pain in the upper middle abdomen.