Spots on both cheeks are not necessarily caused by any organ problem, but may be caused by sun spots, chloasma and age spots. 1. Sun spots: Intense ultraviolet rays can activate tyrosinase in melanoblasts, accelerating melanin synthesis and leading to pigmentation, resulting in sun spots on both cheeks. 2. Melasma: due to long-term sun exposure, mental stress, lack of sleep and other reasons, melasma may occur, and it will appear on both cheeks, with patches of different sizes and clear edges. 3. Age spots: After entering a certain age, the metabolism of skin decreases and keratinocytes accumulate to form age spots, which will lead to the phenomenon of spots on both cheeks. When patients have spots on both cheeks, they should go to regular hospital dermatology department for examination and standardized treatment according to their own causes.