An abnormal gamma-glutamyltransferase of 180 U/L suggests moderately high levels. Gamma-glutamyltransferase, also known as glutamyl transpeptidase, is mainly found in liver tissue, and when the liver is damaged due to various reasons, it will be released into the bloodstream, causing the elevation of glutamyl transpeptidase in the blood. This is why glutamyl transpeptidase is commonly used as a routine indicator for checking liver function. The normal range of glutamyl transpeptidase is 11-50 U/L for men and 7-32 U/L for women. In summary, γ-glutamyl transpeptidase 180 U/L is not normal and is moderately elevated, suggesting the possibility of liver function impairment. Elevated glutamyl transpeptidase can also be seen in hepatobiliary diseases such as extrahepatic bile duct obstruction, primary liver cancer, pancreatitis, pancreatic cancer, kidney disease, and prostate cancer. Elevated gamma-glutamyltransferase alone cannot determine the presence of liver function abnormality, but also needs to be combined with other indicators in liver function tests and imaging tests to make a comprehensive judgment. It is recommended to go to the hospital and ask your doctor to make a judgment if you have abnormalities of glutamyl transpeptidase.