Gevaldi is the trade name and generic name of Metformin Hydrochloride, which can reduce gastrointestinal adverse effects when taken after a meal than before a meal. Metformin hydrochloride tablets can reduce hepatic glucose production and inhibit intestinal glucose absorption, improve insulin sensitivity, and is suitable for type 2 diabetes mellitus that is not well treated by diet and exercise alone. Metformin hydrochloride tablets can be taken before or after meals, taking before meals may cause nausea, vomiting, abdominal distension, diarrhea and other gastrointestinal discomfort, taking after meals can reduce the occurrence of such adverse reactions. It should be noted that the drug is contraindicated in patients with hypersensitivity to the drug, severe renal failure, severe infection, trauma, acute metabolic acidosis, hepatic insufficiency and so on. Patients who need to be treated with metformin hydrochloride are advised to use the drug under the supervision of a doctor.