The common causes of fluid swelling and pain in the wrist are synovitis, gouty arthritis, rheumatoid arthritis and other diseases. Different causes of the disease, its treatment method also exists differently. The main thing is to carry out general treatment, drug treatment and so on. 1. Synovitis: If there is fluid, swelling and pain in the wrist due to synovitis, non-steroidal anti-inflammatory drugs such as ibuprofen and diclofenac sodium can be applied under the guidance of a doctor to relieve pain and discomfort. The application of cephalosporins, penicillins and other anti-infective drugs, to promote the inflammation subside, reduce clinical symptoms. 2. Gouty arthritis: If there is fluid accumulation, swelling and pain in the wrist caused by gouty arthritis, you can be instructed by your doctor to apply anti-inflammatory and analgesic drugs such as etoricoxib and diclofenac sodium. Cooperate with the application of drugs such as febuxostat and allopurinol to inhibit uric acid production. Application of benzbromarone and other drugs to promote uric acid excretion, improve clinical symptoms. 3. Rheumatoid arthritis: If rheumatoid arthritis is caused by the wrist with fluid, swelling and pain, you can follow the doctor’s instructions to apply antibiotics such as erythromycin and penicillin to be treated. The pain is serious, can apply ibuprofen, aspirin and other anti-inflammatory analgesic drugs. If necessary, the doctor should guide the application of prednisone, dexamethasone and other glucocorticoids to be treated. Wrist with fluid swelling and pain, should seek medical attention as soon as possible, after clarifying the cause, to give targeted treatment.