There is no special medicine for the treatment of anal fistula, and antibiotics (such as penicillin) can be used to treat the complication of infection, and also through general treatment, surgical treatment and so on. 1. Antibiotics: anal fistula is generally not treated with medication, when symptoms such as perianal infection occur, antibiotics are needed to control the infection, commonly used drugs are penicillin, amoxicillin and so on. 2. General treatment: usually drink more water, eat more fiber-rich food, regular bowel movements, develop good bowel habits, keep the stool smooth, clean the perianal area in a timely manner to prevent infection. 3. Surgical treatment: low anal fistula can be opened by fistulotomy to promote wound healing; high simple anal fistula can be treated by hanging wire therapy; low simple anal fistula can be treated by anal fistulotomy. It is recommended that the patient timely consultation and treatment, strictly comply with the doctor’s prescription medication.