There are many kinds of sedative sleeping drugs, and the commonly used ones in clinical practice are eszopiclone, alprazolam, clonazepam, diazepam and lorazepam. Sedative drugs may produce dependence when applied for a long time, and also have inhibitory effect on the brain, it is not recommended to be applied for a long time, and clinically, it is mainly applied to patients with severe sleep disorders. Sleep disorders can be clinically caused by a variety of diseases, such as neurasthenia, patients can appear, mild patients mainly oral glutamine, tranquilizing the brain liquid, blood and brain particles to regulate. Can also be adjusted through lifestyle, such as aerobic exercise before going to bed, listen to gentle music, avoid excessive excitement, avoid drinking coffee and strong tea before bedtime, may improve insomnia. Small doses of sedative medication may also be considered when results are less than optimal. Sleep disorders can occur if the patient has an anxiety disorder or if the patient is depressed. Patients with anxiety disorders have difficulty sleeping and are treated with oral tamsulosin and buspirone. Patients with depression who are prone to early awakening during sleep are treated with oral citalopram and, if necessary, small doses of sedative medications.