Principles of treatment for lymphoma

  Malignant lymphoma is an immune cell tumor of lymphatic tissue in lymph nodes and extra-nodal sites, derived from the malignant transformation of lymphocytes or histiocytes. Although malignant lymphoma is relatively rare in China, the number of new cases has been increasing year by year in recent years, at least more than 25,000 cases per year, while the incidence rate in western countries such as Europe, America and Australia can be as high as 11/100,000~18/100,000, slightly higher than the sum of all types of leukemia.  1, Hodgkin’s disease treatment principles (1) ⅠA, ⅡA stage: radiation therapy is the main treatment, if there is a large mediastinal mass, chemotherapy and radiation therapy should be used to integrate; pathology for lymphocyte decompensation type, the application of whole lymph node radiation.  (2) Stage IIB: whole lymph node radiation is generally used, and combined chemotherapy alone may also be used.  (3)Ⅲ1A: Radiation therapy alone.  (4)Stage III2A: Combined radiation and chemotherapy.  (5) Stage IIIB: chemotherapy alone or chemotherapy plus radiotherapy.  (6) Stage IV: chemotherapy alone 2. Treatment principles of non-Hodgkin’s lymphoma (1) Low-grade malignancy: ①Stage I and II: Mostly radiotherapy is used, and the application of chemotherapy after radiotherapy cannot solve the problem of recurrence even after several years.  ②Stage III and IV: Most of them use chemotherapy.  (2) Moderate malignancy: Stage I patients can be treated with radiotherapy alone. Stage II and above are treated with chemotherapy regimen based on adriamycin.  (3) Highly malignant: lymphoblastic lymphoma with leukemia-like treatment regimen.  3. The indications for surgery as a treatment for malignant lymphoma are very limited, and the cure rate is also low, and often needs to be supplemented with radiotherapy or chemotherapy.  4., Hematopoietic stem cell transplantation treatment is better than chemotherapy.