Duodenal bulbitis is not considered a serious disease, but it should be taken seriously, and follow the doctor’s instructions for standardized treatment. Duodenal bulbitis is a non-specific inflammatory disease that occurs in the duodenal bulb, usually manifested as epigastric pain, flatulence, nausea, vomiting, acid reflux, black stools, etc. It is not a very serious disease, usually does not lead to serious life-threatening, but it should be actively given treatment. Duodenal bulimia should be treated with acid inhibitors (such as omeprazole) and mucosal protectants (such as bismuth potassium citrate), and if Helicobacter pylori infection is present, quadruple therapy can be given, such as omeprazole, amoxicillin, clarithromycin, bismuth potassium citrate and other medications. Daily diet for duodenal bulbitis prohibits strong tea, coffee, tobacco, alcohol and other stimulating foods, and it is recommended to seek medical attention in time and follow the doctor’s instructions to avoid further aggravation of the condition.