Knee pain may be a symptom of many diseases, such as osteoarthritis, rheumatoid arthritis, gouty arthritis, etc. It is not necessarily treated with calcium supplements. If it is caused by osteoporosis or calcium deficiency, calcium carbonate, calcium citrate, calcium gluconate, etc. can be used. 1. If the pain is caused by osteoarthritis, non-steroidal anti-inflammatory drugs such as ibuprofen and aspirin can be used for analgesia, and drugs such as aminoglucose sulphate and other cartilage-nourishing drugs can also be used for treatment. 2. If the pain is caused by rheumatoid arthritis, in addition to the above non-steroidal anti-inflammatory analgesic drugs, you can use glucocorticosteroid therapy, which can quickly relieve the symptoms of joint swelling and pain, commonly used trichostatin, betamethasone acetate and so on. 3. If the pain is caused by gouty arthritis, colchicine is the first choice to relieve pain, followed by indomethacin, ibuprofen and other non-steroidal anti-inflammatory analgesic drugs. 4. If the knee pain is caused by osteoporosis, calcium supplements, such as calcium carbonate, calcium citrate, calcium gluconate, etc., can be used. It is recommended to consult a doctor in time to find out the cause of the disease and then treat it, and the use of medication should be guided by a doctor.