Empty abdominal pain is common in duodenal ulcer, but it may also be related to other diseases such as chronic gastritis, which need to be combined with the pattern of their abdominal pain episodes and some tests to make a comprehensive judgment. Duodenal ulcer patients can be manifested as regular episodes of abdominal pain, this pain tends to attack before meals or in the middle of the night, can be relieved after eating, and eating behavior has obvious regularity, it is due to Helicobacter pylori infection, gastric acid secretion increase and other factors, clinically can be diagnosed by gastroscopy. Patients with chronic gastritis can also exhibit abdominal pain after using drugs such as aspirin on an empty stomach or drinking alcohol on an empty stomach, but patients with chronic gastritis cannot get significant relief from abdominal pain after eating, chronic gastritis can also be diagnosed by gastroscopy. In addition to the above factors, other diseases may also lead to abdominal pain. If the symptoms of abdominal pain persist without relief, please consult a doctor as soon as possible and ask the doctor to deal with it.