Chinese and foreign oncologists agree that cancer has complex and variable characteristics and diversity of clinical manifestations. Generally speaking, if the first diagnosis is inaccurate and causes treatment failure, the consequence is to bring a lot of suffering and even life-threatening to the patient. The first treatment of cancer is life-critical, and the choice of treatment plan should not only save and prolong the patient’s life, but also consider the quality of life after recovery. Therefore, it is crucial to formulate a comprehensive treatment plan through the first diagnosis to improve the cure rate and survival rate. The so-called first treatment refers to the time when the patient receives the first treatment, and its method must be moderate, which means that the appropriate treatment plan should be adopted according to the location of the tumor, tissue type and biological characteristics of the cancer tumor, just right. Unlike other diseases, cancer has the characteristics of easy infiltration and metastasis. If cancer patients can actively cooperate with doctors for timely and effective treatment, it is possible to achieve satisfactory results and some of them can even be cured. However, from the current situation of the society, there are many people who have cancer, but their family members are worried that the patient cannot accept the shock of getting cancer suddenly, so they adopt a strict attitude towards the patient and do not allow the patient to receive treatment in oncology hospitals or oncology doctors, but send the patient to general general hospitals for treatment, so that the patient steps into the wrong area, not only the treatment effect is unsatisfactory, but also the best treatment time is missed, so that the curable tumor is lost. This not only leads to unsatisfactory treatment effect, but also misses the best time for treatment, making curable tumors lose the chance of cure. If cancer treatment fails for the first time, due to local recurrence or distant metastasis, and then go to tumor specialist hospital or seek treatment from professional doctors, the result will not be satisfactory no matter what method is used because the appropriate treatment time is lost. Therefore, whether the first treatment is correct or not is of decisive significance for cancer patients, and it is worthy of the common concern of the whole society. On the issue of treating cancer correctly, besides having a positive attitude and establishing confidence in winning, we should also pay great attention to the means and methods of treatment. If you have cancer, you should seize the time and treat it actively so as not to lose the good opportunity of treatment. Whether the first treatment is successful or not is directly related to the life and death of the patient. The main reason for the failure of treatment of many cancer patients is not because of cancer itself, but due to misdiagnosis, wrong treatment or inappropriate treatment, resulting in the delay of the disease and losing the chance of complete cure, which also causes great difficulties to the future treatment, and some of them can only take remedial measures and cannot be given a radical cure. The first treatment plays a decisive role in the prognosis of cancer patients, and if the first treatment plan is scientific and reasonable, patients can get satisfactory results. For example, if patients with early-stage nasopharyngeal cancer, esophageal cancer, stomach cancer, breast cancer, rectal cancer, cervical cancer, etc. are treated scientifically and reasonably, their cure rate can be over 90%. Even for patients with mid- to late-stage cancer, they can be partly cured and partly relieved, improved and prolonged after comprehensive treatment. However, if the first diagnosis and treatment is not proper, it will not only bring great pain and economic loss to patients, but also endanger their lives. Thus, it seems that cancer patients and doctors should pay special attention to the first diagnosis and treatment. As a patient, you should not rush to the doctor, and you should not believe in some charlatans in the society, and those advertisements which are blown out of proportion, such as the ultimate prescription, partial prescription, ancestral secret formula or “cure for cancer”. You should be careful to choose oncology hospitals or doctors with oncology specialties in large hospitals for medical treatment. As a doctor, you must be especially cautious in treating cancer patients, inquiring about their conditions in detail, making accurate diagnosis carefully, adopting today’s recognized comprehensive cancer treatment methods, designing scientific and reasonable comprehensive cancer treatment cases, and improving the long-term efficacy and survival rate of cancer patients.