You can take acetaminophen, ibuprofen or anti-inflammatory medication if your tooth hurts after the second sealing. It is necessary to use the medication under the supervision of a doctor. Teeth very painful after the second sealing can take acetaminophen, ibuprofen and other pain medications, if the slow relief after 3-5 days, then it may be a normal reaction. If there is no relief, or the symptoms worsen, the pulp cavity may be pulp tissue has not been removed cleanly, then only by taking medication is not enough, you need to go to the dentist to remove the residual pulp fibers. In addition, worsening pain may also be a result of filling leakage and bacterial infection of the root canal from saliva, in which case anti-inflammatory medications, such as cephalosporins, can be taken, along with painkillers. If the dose of sterilizing medication placed during root canal treatment is large and produces irritation, it can also lead to symptoms of worsening pain. In this case, the medication alone can not fully control the pain, and it is necessary to seek medical attention for medication change treatment. It is recommended that patients seek medical attention in a timely manner to identify the cause and decide on the treatment method under the guidance of the doctor. Pay attention to take drugs under the guidance of the physician.