Commonly used drugs for dehydration and lowering cranial pressure include mannitol, glycerol fructose, furosemide, albumin, and also adrenocorticosteroids. Mannitol is a short-acting hypertonic dehydrating agent with rapid onset and good effect, and relatively short duration. Patients may experience electrolyte disorders after application, so it is important to review the ions in a timely manner. Glycerol fructose is also a drug to lower intracranial pressure, its mechanism of action is similar to mannitol, but glycerol fructose is a long-acting dehydration, lowering cranial pressure drugs, the duration of action is long, and the effect of dehydration is more stable, causing electrolyte disorders is less dangerous. Albumin can be used for patients with low albumin, and it can replenish albumin and play the role of osmotic dehydration at the same time. Furosemide is a diuretic and promotes fluid excretion in the body, which can also play a role in lowering cranial pressure.