The chances of cancerous transformation of vulvar leukoplakia depends on the type of vulvar leukoplakia. The chances of cancerous transformation of vulvar chronic lichen simplex moss are very small, and the chances of cancerous transformation of vulvar sclerosing moss are slightly higher. Leukoplakia, also called vulvar leukoplakia, is a pigmented change in the vulva of women, and can be divided into vulvar chronic lichen simplex and vulvar sclerosing moss, and vulvar chronic lichen simplex has a very low chance of malignant transformation. Most patients can control the development of the disease through local medication and physical therapy. Vulvar sclerosing moss is a difficult disease to cure. It is usually treated with topical medication and physical therapy to control the progression of the disease, but many patients will have recurrent symptoms after treatment. 2% to 5% of patients may become cancerous, and the more common one is non-human papillomavirus-associated squamous carcinoma. If you are suffering from vulvar leukoplakia, it is recommended that you consult a doctor in a timely manner, complete the relevant examinations, clarify the cause of the disease under the guidance of a professional doctor, and target treatment. It is recommended to follow the doctor’s instructions for long-term follow-up, and if abnormal changes occur, they should be treated promptly.