Generally speaking, men begin to decline in sexual function at around 45 years of age, which is closely related to the physical quality of the individual, and may also be related to diabetes, hypertension and other diseases. With age, generally in 40 to 50 years old, male androgen secretion decreases, which will lead to a decline in sexual function can be manifested as erectile dysfunction, premature ejaculation and so on in serious cases. Some people are in better physical condition, so their sexual function declines relatively slower. Diabetes, hyperlipidemia, hypertension and other chronic diseases, may make men’s penile vasculopathy, such as due to the elevation of blood lipids will lead to penile cavernous small arteries vascular cholesterol buildup and atherosclerosis, diabetes may damage the nerves that have the role of conduction, which leads to the decline of sexual function. It is recommended that patients should usually develop good living habits, actively control chronic diseases, and seek timely medical treatment when uncomfortable symptoms occur.