In general, stomach medicines that protect the gastric mucosa can be taken together with cold and flu medicines, and there is no special interaction between the two. Clinically, it includes drugs that inhibit gastric acid secretion, protect gastric mucosa, anti-Helicobacter pylori, etc. The commonly used ones are proton pump inhibitor omeprazole, bismuth potassium citrate, aluminum thiosulfate, and so on. Cold and flu medicines are commonly used to reduce fever and improve respiratory symptoms, such as acetaminophen and compound aminophenolane, etc. In addition, some proprietary Chinese medicines, such as Banlangen, Lianhua Qingdian capsule, and cold and flu granules, etc. are also commonly used. Generally speaking, there is no special drug interaction between stomach medicine and cold medicine, and they can be taken together, but it is still necessary for the clinician to analyze the specific medication and the patient’s own situation. Therefore, if you are not sure whether there is any interaction between stomach medicine and cold medicine, you should consult your doctor.