If the adrenal gland is removed unilaterally, the opposite side is healthy, usually not much effect, if both adrenal glands are removed. There is a certain impact on the human body. The adrenal gland can secrete a variety of hormones including steroid hormones, epinephrine, norepinephrine, dopamine and so on. There are two adrenal glands in the human body, if one side is removed and the other side is functioning well, the impact is generally not significant. However, if both sides of the adrenal gland are removed, it may lead to changes in the levels of the above hormones in the body. Different hormones can be involved in different human activities; for example, steroid hormones are mainly secreted by the adrenal cortex, which are involved in the body’s sugar metabolism, fat metabolism, protein metabolism, stress response, etc. They are essential hormones to maintain life activities, and the lack of which may affect the metabolism of nutrients in the body.