Antithyroglobulin antibody is an autoantibody belonging to patients with autoimmune thyroid disease. The antibody is 296 IU/ml, which is beyond the normal range, but the severity of the condition should not be judged solely on the basis of this indicator, because many thyroid diseases nowadays have high antithyroglobulin antibody, and the severity of the condition should be judged comprehensively in combination with other thyroid function indicators. Under normal circumstances, the range of anti-thyroglobulin antibodies should be <60IU/ml (chemiluminescence method). According to the current value, the anti-thyroglobulin antibody value has exceeded the normal range, suggesting that the thyroglobulin antibody is high. This may be due to diseases such as Hashimoto's thyroiditis, and the severity of the disease cannot be determined solely on the basis of high anti-thyroglobulin antibodies. Antithyroglobulin antibodies may also be high in patients with many other immune disorders, such as dry syndrome, and it is not possible to determine whether antithyroglobulin antibodies of 296 IU/ml are serious. If high anti-thyroglobulin antibodies are detected, a number of tests should be performed at a later stage to determine the type of thyroid disease, including thyroid ultrasound, tumor markers, and pathological biopsy, from which malignant lesions can be ruled out.