Children’s soles of the feet peeling skin, can be considered tinea pedis, psoriasis palmoplantar pustulosis or eczema, etc., through the general treatment and medication to promote the healing of the disease. 1. Tinea pedis: the condition of peeling of the soles of the feet can occur. Parents need to pay attention to the child to wear breathable shoes and socks, keep the feet dry; do not share shoes and socks, bath tub, foot basin and other household items. If necessary, topical miconazole clobetasol cream can be used as prescribed by the doctor. 2. Psoriasis palmoplantar pustulosis: it can be induced by both genetics and environment, need to control the symptoms in time, can be used externally to promote the formation of dumpling keratin; if necessary, follow the doctor’s advice to use methotrexate and other immunosuppressant or biologic agent treatment. Pay attention to the child’s psychological treatment, and at the same time to avoid the aggravating factors such as fatigue, mental stress. 3. Eczema: the above phenomenon can also occur, can be used topically hydrocortisone cream, dieldrin cream and other topical glucocorticosteroids; itching is severe, consider the use of loratadine, cetirizine and other antihistamines; should also pay attention to clothing loose, cool, after the bath use of emollients to restore the skin barrier. All of the above medications should be used under the guidance of a physician to avoid self-medication. There are many other causes of foot peeling in children, and it is recommended to consult a physician in a timely manner to be evaluated by a specialist for treatment or therapy.