The third dose of the new coronavirus vaccine may not have a significant effect on the thyroid gland. In principle, the third dose of the new coronavirus vaccine can be administered for chronic diseases including thyroid gland, as long as the disease is not in an acute flare-up period. The new coronary vaccine is a vaccine against the new coronary virus. Currently, most of the new coronary vaccines are inactivated vaccines, which mainly activate the body’s immune system to immunize against specific viruses. If the body is in the onset of the disease and the body’s immune system is more active, the new coronary vaccine is not generally recommended. Thyroid diseases are endocrine system diseases, such as thyroiditis, thyroid nodules, etc. If you have an acute attack of the above diseases, it is also not recommended to receive the new crown vaccine, you can wait until the thyroid gland is back to normal after the treatment before considering the third vaccination of the new crown vaccine. The patient should inform the doctor about the specific condition of the thyroid gland before vaccination, and if the doctor permits the vaccination, the patient should strengthen the observation of his own symptoms after vaccination, and should consult the doctor in time if any uncomfortable symptoms appear.