Difference in action between nimodipine and nicergoline

Nimodipine and Nicergoline are two different categories of drugs. Nimodipine is a cerebral vasodilator, while Nicergoline is a cerebral nutrient metabolizer. 1. Nimodipine is a dihydropyridine calcium antagonist, which can easily pass the blood-brain barrier and act on the cerebral blood vessels and nerve cells, and has the functions of dilating blood vessels, improving cerebral circulation and relieving head pain, increasing cerebral blood flow without affecting cerebral metabolism. It is used in ischemic cerebrovascular diseases, especially suitable for the prevention and treatment of neurological deficits caused by local ischemia after subarachnoid hemorrhage due to arterial spasm, as well as strokes, migraines, etc., and also has a certain degree of efficacy in sudden deafness. 2. Nicergoline: It is a semi-synthetic alkaloid with alpha receptor blocking and vasodilating effects, which can enhance the metabolism of brain cells, promote the utilization of oxygen and glucose, enhance the synthesis of brain proteins, and improve the brain function, and it has a good effect on some acute and chronic cerebral vascular and cerebral metabolic dysfunction. Used to improve the sequelae of cerebral infarction caused by low intention and affective disorders, acute and chronic peripheral circulatory disorders, also applies to vascular dementia, especially in the early treatment of cognition, memory and other improvements, and can reduce the severity of the disease. All of the above medications should be used under the guidance of a physician, and individuals should not use them on their own to avoid adverse effects.