The appearance of clear and long urine may be normal or abnormal. The former is usually seen in large amounts of water and alcohol, mainly because drinking a lot of water can lead to a decrease in plasma osmolality, thus reducing the secretion of antidiuretic hormone, resulting in an increase in the volume of urine, the color of urine becomes clear. Alcohol contains a large amount of ethanol, which can inhibit the secretion of antidiuretic hormone, thus causing the urine volume to become more and lighter in color, which needs to be considered a pathological factor. Usually seen in some endocrine diseases, such as central uremic syndrome, mainly hypothalamic lesions lead to antidiuretic hormone synthesis and secretion of reduced, thus causing increased urine volume, urine clear long. Such as routine urinalysis can be found in hypotonic urine, urinary sodium fraction decreased changes, some renal diseases can also cause urine clear long, such as renal diabetes insipidus. Mainly renal tubular antidiuretic hormone receptor function changes, its sensitivity to hormones is reduced, resulting in the weakening of the role of antidiuretic hormone, so that the urine volume increased, the urine clear long.