The treatment of otitis media leading to tympanic membrane perforation varies from person to person: 1. For patients with acute otitis media with tympanic membrane perforation, oral cephalosporin and erythromycin antibiotics should be the main treatment, and local oxyfloxacin ear drops can be used, and after the inflammation is controlled, the tympanic membrane perforation will generally heal on its own in about two weeks; 2. For patients with chronic purulent otitis media with tympanic membrane perforation, antibiotics should be used first to bring the inflammation under control, followed by early The tympanic membrane should be treated with antibiotics to control the inflammation, followed by early treatment with tympanic membrane repair and ossicular chainplasty. The specific medication should be combined with the clinical situation and guided by the doctor’s interview.