Dry, itchy, flaky thumbs should be treated with medications based on the cause, which is mainly caused by skin dehydration, ringworm, vitamin deficiency, eczema and other causes. You can use emollient creams, antifungal, glucocorticoid creams and other drugs for treatment. 1. Dry skin: If frequent hand washing, or the use of alkaline detergents, etc. lead to a reduction in the skin surface oil, causing dry skin, itchy skin and other symptoms. At this time, you can use topical moisturizing creams such as urea ointment, petroleum jelly ointment and other drugs. 2. Ringworm: ringworm caused by infection of dermatophytes, most of the anti-fungal drugs for treatment, such as oxiconazole nitrate ointment, ketoconazole ointment, econazole ointment and other drugs, if necessary, also need to be combined with oral medication, such as itraconazole capsules and so on. 3. Lack of vitamins: for the lack of vitamins caused by dry itchy skin on the thumb, most of them do not use the potion for treatment, usually in ordinary life, eat more vitamin-rich vegetables and fruits. 4. Eczema: If the thumb has eczema, there will also be dry itchy skin. At this time can be used externally glucocorticoid ointment such as mometasone furoate, hydrocortisone butyrate ointment and other drugs, if necessary, can be combined with oral antihistamine drugs such as loratadine. Thumb dry itchy skin, it is recommended to go to the hospital for examination, the doctor will be based on the clinical symptoms of the diagnosis, clear cause of the disease and timely symptomatic treatment. Drugs should be used in accordance with medical advice.