Psoriasis is a chronic relapsing inflammatory disease with genetic predisposition. 1, psoriasis is a chronic recurrent disease When it comes to chronic recurrent, many patients do not understand, and even angry. Modern medicine is developing rapidly, why can’t we study psoriasis? Why can’t it “break the root”? Psoriasis does affect the quality of life of patients, especially patients with severe psoriasis, patients can imagine the disappointment of not being able to “break the root”. But patients have to face the reality with great regret. To this day, researchers around the world have conducted numerous scientific studies on psoriasis, and have found that psoriasis is a polygenic disease in which genetic and environmental factors interact. This means that people with genetic factors can develop psoriasis in response to certain environmental factors. Environmental factors include upper respiratory tract streptococcal infections, endocrine factors, psycho-neurological factors, immune factors, living habits, medication factors and seasonal climate. Genetic factors are unchangeable, environmental factors control is good, psoriasis skin damage will be relieved or even disappear; environmental factors control is not good, psoriasis skin damage will be aggravated or relapse. Part of the patients with a certain incidence of skin damage completely subside, can be several years without the onset of the author has even seen more than forty years without recurrence of the patient. Therefore, although psoriasis is a chronic recurrent disease, the interval between recurrences can be as long as several years, or even decades. 2, psoriasis is an inflammatory disease, some people will ask, “since it is inflammatory, then use anti-inflammatory drugs will not be on the line,” “anti-inflammatory drugs with cephalosporin okay?” This is a problem often encountered in clinical work. In fact, many people have a misunderstanding of the concepts of “inflammation” and “anti-inflammatory drugs”. They think that inflammation is caused by bacterial infection, and anti-inflammatory drugs are antibacterial drugs. In fact, inflammation (commonly known as “inflammation”) is the body’s defense response to stimuli, can be caused by pathogenic microorganisms (such as viruses, bacteria and fungi, etc.), but also by physical factors (such as high temperature, low temperature and sun exposure, etc.), chemical factors (such as strong acid, strong alkali) or allergic reactions and other non-infectious factors. Caused. Inflammation can manifest as redness, swelling, heat, pain and dysfunction. It follows that fighting inflammation does not necessarily require antibacterial drugs. And the term anti-inflammatory does not exist in medical terminology. Inflammation in psoriasis, which can occur in the skin or in the joints, is a non-infectious inflammation, so antimicrobials are applied only if the psoriasis patient has a combined bacterial infection, while anti-inflammatory treatment in other cases relies on non-steroidal anti-inflammatory drugs (ibuprofen), steroidal anti-inflammatory drugs (glucocorticosteroids), other medications, or physical therapies such as phototherapy. The choice of treatment options varies depending on the location of the disease, the severity of the disease and the specific requirements of the patient. It is important to note that the inflammation of psoriasis can occur in the joints and is called “psoriatic arthritis” or “arthropathic psoriasis”. Most patients have psoriasis skin damage first, and then joint inflammation; there are also a few patients who have joint inflammation first, and then skin damage, and joint symptoms are often parallel to skin symptoms. 3.Psoriasis has genetic tendency Psoriasis has genetic tendency and family aggregation. The risk of psoriasis in the next generation of psoriasis patients is higher than that in the next generation of non-psoriasis patients. In recent years, there have been many studies on the genetics of psoriasis, and some psoriasis susceptibility genes have been found. However, there is still no gene that can completely explain the cause of psoriasis, and prenatal diagnosis based on genetic testing is not yet possible. In fact, many common human diseases are diseases with genetic predisposition, such as hypertension, diabetes and high myopia, etc. People with susceptibility genes for a certain disease are not 100% morbid, but will develop the disease only under the effect of certain triggers. Since it is a fact that whether or not a person is born with a susceptibility gene cannot be changed, what the next generation of psoriasis sufferers can do is to adjust their mindset and avoid triggers to avoid the onset of psoriasis. In conclusion, psoriasis has a complex etiology and pathogenesis, which is the result of the joint action of genetic and environmental factors. Despite the rapid development of modern medicine, it is still impossible to change the status quo of psoriasis as a chronic relapsing inflammatory disease, so it cannot be completely cured.