Rapamycin dosage: oral, for renal transplant patients, the first loading dose should be 6 mg and the maintenance dose is 2 mg/day, usually once daily. For patients over 13 years of age but weighing no more than 40 kg the dosage should be calculated on the basis of body surface area, with a loading dose of 3 mg/m and a maintenance dose of 1 mg/m/day. The maintenance dose should be reduced by 1/3 in patients with hepatic impairment. Rapamycin is an anti-immunosuppressive drug and can be used in combination with cyclosporine and other drugs in patients with renal suppression. The administration of this product can lead to nausea, dizziness, headache, arthralgia, nosebleeds, thrombocytopenia, leukopenia, hyperglycemia, hypercholesterolemia, hypokalemia, hypomagnesemia and other adverse reactions. Note that it is contraindicated in patients who are allergic to this product, sirolimus. Patients must use the drug under the guidance of a professional physician and strictly comply with medical advice.