High HDL cholesterol is a good thing because it is the only lipoprotein that is relatively higher and helps prevent atherosclerosis. Some patients with low HDL cholesterol should routinely take statin drugs to raise HDL cholesterol if they have high risk factors for cardiovascular disease, such as Rosuvastatin and Atorvastatin. Generally speaking, patients who do not smoke or drink alcohol and who have a regular diet and lifestyle are prone to have high HDL cholesterol.