Whether ALT 82 U/L is serious or not cannot be generalized. If it is caused by physiological reasons, it is not serious; if it is caused by diseases, such as alcoholic liver disease, viral infection of the liver, biliary tract diseases, etc., it tends to be more serious. 1. Physiological reasons: may be due to overwork, late at night, high protein diet or strenuous exercise caused by the liver function will be slightly transient damage, resulting in alanine aminotransferase increased, but will gradually return to normal. 2. Pathologic causes: alcoholic liver disease, viral infection of the liver, biliary tract diseases, etc. can cause elevated ghrelin. (1) Alcoholic liver disease: including alcoholic hepatitis or alcoholic cirrhosis, often due to long-term alcohol abuse caused by significant reduction in liver function, which leads to a more serious increase in ASTE. (2) Viral infection of the liver: most commonly seen in hepatitis B virus, the virus tends to replicate in large quantities in the liver, leading to damage of liver cells and causing elevation of ghrelin. (3) Biliary tract diseases: such as gallstones and cholecystitis, biliary tract obstruction often occurs, resulting in enlarged liver parenchyma cells and large necrosis, causing elevated ghrelin. Glutamine transaminase 822U/L if it is caused by disease, must actively cooperate with the doctor to avoid aggravation of the condition.