When a woman reaches the age of 40 or more, she enters the peri-menopause period, at this time there is always the possibility of menopause, whether or not menopause is the first manifestation of menopause, in general more than six months without menstruation, or the original menstrual cycle has three cycles without menstruation, then the likelihood of menopause is high. In addition, we can check the blood, if the luteinizing hormone and follicle stimulating hormone are elevated, more than 40miu/ml, and there is a decrease in estrogen and progesterone, generally lower than the level of the normal basal value, which is certain that it is basically the menopause, however, some people in the menopausal one year or less may have a period once in a while, which is not to be worried about, and it is a normal phenomenon, which is caused by the development of a follicle once in a while, and the development of a follicle in this time. This is also a normal phenomenon and may be caused by the occasional development of an egg follicle. At this time, most people will also show symptoms of menopause, including hot flashes, night sweats, irritability, easy to get angry, and poor sleep at night.