Loss of sense of taste may be caused by facial nerve paralysis, lingual inflammation, etc. It can be treated by nutritive nerve medication, facial nerve decompression, and rinsing with sodium bicarbonate solution to restore the sense of taste. 1. Facial nerve palsy: the sense of taste is mainly innervated by the facial nerve. Facial nerve palsy caused by various reasons, such as viral infection, stroke, brain tumor, etc., may lead to the loss of the sense of taste. In the treatment of primary disease, patients can be given vitamin B₁ and vitamin B₁₂ and other nutritive nerve drugs. Some patients with unsatisfactory drug treatment and serious conditions can also be treated with surgical procedures such as facial nerve decompression. 2. Tongue inflammation: Generally, the symptoms of antibiotic-associated tongue inflammation are abnormal taste or loss of taste, dry mouth and so on. Usually, antibiotics can be stopped as prescribed by the doctor, and local sodium bicarbonate solution can be given to rinse the treatment. Patients are advised to seek medical attention if they experience loss of taste. And use medication under the guidance of the doctor, not private medication, so as not to cause adverse consequences.