Elevated retinol binding protein may be related to kidney disease, overnutritional fatty liver, commonly used drugs are antihypertensive drugs, glucocorticosteroids, lipid-lowering drugs, vitamin B and so on. 1. Elevated retinol binding protein caused by kidney disease: patients can take antihypertensive drugs such as diuretics (furosemide) and calcium channel blockers (such as nifedipine extended-release tablets) under the guidance of doctors, which can reduce the risk of cardiovascular and cerebral vascular disease; glucocorticosteroids, such as prednisone, methylprednisone, etc, which have the effects of anti-inflammation and immunosuppression. 2. The elevation of retinol-binding protein caused by over-nutritional fatty liver disease: patients can take lipid-lowering drugs such as simvastatin, lovastatin and so on as prescribed by the doctor; take vitamin B and so on. Usually also appropriate exercise, increase the body fat consumption, can also make retinol binding protein lower. Patients with elevated retinol binding protein need to go to the hospital in a timely manner, follow the doctor’s instructions to improve the examination, to clarify the cause of the disease, and timely symptomatic.