Closed mouth acne on the face can be removed by general treatment, medication and physical therapy. 1. General treatment: Patients with closed mouth acne are advised to wash their face with warm water, avoid using irritating cosmetics, avoid diets high in sugar, fat and spicy stimuli, and avoid staying up all night. 2. Medication (1) Topical medication: if not accompanied by inflammation or infection, adapalene gel, benzoyl peroxide, etc. can be used externally. (2) Oral medication: If external medication is not effective, or if it is more serious, oral isotretinoin capsules can be taken. (3) Physical therapy: If medication is not tolerated, physical therapy can be used, such as photodynamic therapy, chemical peeling therapy, laser therapy radio frequency therapy, etc. If you need to remove the closed mouth acne on your face, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor to carry out active treatment, do not take medication without authorization, to avoid adverse reactions.