Blisters are medically referred to as blisters. Itchy blisters on the hands may be caused by herpes sweat, eczema, ringworm and other factors, which can be removed by general treatment and medication. 1. Sweat herpes: This disease may cause blister-like lesions on the palms of the patient’s hands and is accompanied by an itchy sensation. Topical anti-inflammatory and anti-itching medications such as tretinoin urea ointment and pimecrolimus ointment can be used externally. When itching is obvious, antihistamines such as Benadryl can be used to relieve it. 2. Eczema: The disease is related to infection, immune disorder and other factors, and blister-like lesions may appear on the hands. To timely detach from the allergen, avoid scratching; acute period can be used isacridine solution wet compresses, subacute period can be used zinc oxide paste coated, chronic period can be used urea ointment, mometasone furoate ointment; can also be taken orally loratadine, cetirizine, etc. to stop the itching, and concurrently infected with amoxicillin can be used. 3. ringworm: due to fungal infections, will also be manifested as blisters on the hands of very itchy symptoms. At this time need antifungal treatment, such as external miconazole, clotrimazole ointment. If necessary, oral itraconazole, terbinafine and other drugs. There are many factors that lead to itchy blisters on the hands, and it is recommended that patients seek timely treatment and strictly comply with the doctor’s instructions for medication.