When it comes to taking medication, we all know the familiar phrase: “It’s medicine three times more toxic.” Therefore, many people have the mindset that they can treat their disease without taking medication. For diabetes, a chronic disease that requires long-term medication, what is the impact of using intermittent medication on the condition? Diabetes is mainly a result of defective pancreatic islet function leading to unstable blood sugar in the body, and the body needs to eat every day, which means that sugar is consumed every day. This means that whenever a diabetic eats something there is a chance that it will lead to unstable blood sugar, which is the main reason why diabetics basically need to take medication every day. Of course, as an internal medicine means to control blood sugar, the frequency of medication as well as the amount of medication for patients needs to be determined based on a combination of the function of insulin secretion by the pancreas and the blood sugar level of diabetic patients. However, it is certain that, in terms of long-term benefits, internal medication and insulin injections to control blood glucose will gradually increase in dosage as the patient grows older. Therefore, a sudden discontinuation of medication during diabetes may lead to a rebound of blood glucose in the body and blood glucose fluctuations which is a very disruptive outcome of the disease. Nowadays, for most patients with type 2 diabetes, which is eventually triggered by insulin resistance due to obesity, there is a treatment method that is more effective without medication, weight loss surgery. Surgery adjusts the function of the body’s gastrointestinal tract, reduces nutrient absorption and limits food intake, and restores damaged insulin function through weight loss, thus treating diabetes.