Diffuse cholesteatoma is also a type of cholesteatoma, which is a benign tumor. Diffuse cholesteatoma is a benign tumor that occurs in the middle ear area or the external auditory canal, but the disease is aggressive and may involve a person’s intracranial nerves if the condition is severe and left untreated. The more common causes of diffuse cholesteatoma include congenital and acquired factors; congenital factors are usually formed during embryonic life, while acquired factors are often associated with inflammatory infections as well as surgery and trauma. With cholesteatoma diffuse cholesteatoma, most patients have no obvious symptoms, but those whose disease progresses at a faster rate may suddenly feel blockage in the ears, ear pain, and it can affect hearing. If currently found to have diffuse cholesteatoma, worried about hearing loss, damage in the ear, should be timely anti-infection, if necessary, need to carry out surgical treatment, such as papillary opening surgery, tympanoplasty, etc., specific should be carried out under the guidance of a professional physician.