Tooth extraction is a common oral surgery, however, female patients need to pay attention to many issues when performing tooth extraction due to their physiological peculiarities, so let’s learn some precautions for women to treat their teeth and extract teeth. Menstruation is a physiological change unique to women. In addition to maintaining female characteristics and reproductive functions, this change often affects the bleeding and clotting mechanism of human blood. According to research, platelets change significantly during menstruation, often decreasing on the first day of menstruation and only rising back to their original number on the third or fourth day. In addition, during menstruation, the human endometrium can release more tissue-activating substances, which can activate fibrinolytic enzyme in the blood into fibrinolytic enzyme with anti-coagulant effect, so that the human body has a greater tendency to bleed and the blood does not easily clot to form blood clots. After tooth extraction, the contact between the wound and saliva causes slow wound healing and makes it easy for bacterial infection and bleeding to occur. Therefore, surgery or tooth extraction during menstruation may cause more bleeding. According to the analysis of clinical data, it is confirmed that the 14th day of menstrual cycle is the best time for women to have their teeth extracted. At this time, the wound heals quickly and well, bacterial infection is less likely to occur, and the pain is lighter. Therefore, it is best for women to have their teeth extracted on the 10th day after menstruation. Although pregnant women are not affected by menstruation, women in the first trimester often have pregnancy reactions such as nausea and vomiting, and are prone to miscarriage during tooth extraction, while women in the last trimester are prone to premature birth under the stimulation of tooth extraction, so tooth extraction is also not advisable, and it is safer to extract teeth only in the fourth, fifth and sixth trimester. In cases of habitual miscarriage or premature birth, tooth extraction is not advisable throughout pregnancy. When tooth extraction is necessary, it is best to choose between the 3rd and 6th months of pregnancy, and progesterone 10 mg should be injected intramuscularly every day for 1-2 days before and after tooth extraction to eliminate the fear of tooth extraction to avoid miscarriage and premature delivery. Tooth extraction during breastfeeding should be done with caution because it is usually done with anesthesia, and the ingredients of the anesthesia will be absorbed by the child with the breastfeeding lotion at this time, which is not good for the neurological growth and development of the child. If extraction is necessary, it is best not to breastfeed for 72 hours after the extraction and wait until the anesthetic is basically metabolized after 72 hours before breastfeeding. It is also worth paying high attention to the extraction of teeth for menopausal women, because patients in this period often have a very strong role in their hearts, are not very stable emotionally, and are fragile mentally, mainly because they suspect that there are residual roots in the mouth after extraction, suspect that the wound is inflamed or may be infected with other diseases due to incomplete sterilization in the hospital’s subjective imagination, and suspect that they have caused many injuries to themselves due to the doctor’s technical deficiency or improper operation. The patient may also suspect that the doctor’s inadequate technique or improper operation will cause him/her a lot of harm. Therefore, before the extraction, all the concerns must be explained clearly and patiently. In addition, for patients at this stage, the patient should be informed of the longest possible extraction operation time before the extraction, so as to avoid the patient’s distrust of the doctor’s technique due to the slightly prolonged extraction time. When injecting the anesthetic, change the topic of conversation to distract the patient’s attention and prevent adverse clinical manifestations due to excessive tension.