Total prostate-specific antigen (TPSA), which usually ranges from 0 to 4 ng/ml, is an important tumor marker for clinical screening of prostate cancer. The range of normal values for total prostate-specific antigen can be affected by the patient’s age and race. The normal value of total prostate-specific antigen is 0-4 ng/mL. When the total prostate-specific antigen is 4-10 ng/mL, and the ratio of free PSA to total PSA is greater than 0.18, it suggests that the total prostate-specific antigen is still in the normal range and can be observed. A patient with a total prostate-specific antigen value greater than 10 ng/mL suggests an abnormal prostate-specific antigen. Patients with elevated PSA need to go to the urology department for further examination. Ultrasound examination can find out whether there is any space-occupying lesion in the prostate, and transurethral prostate aspiration biopsy and pathological examination can exclude the presence of urological prostate tumors.