Urine proteinuria occult blood 3 +, suggesting proteinuria and hematuria, is divided into physiological and pathological conditions. Physiological generally do not need treatment, pathological common in acute and chronic nephritis, nephrotic syndrome, lupus nephritis and other diseases, usually can be given ACEI or ARB drugs, hormones, immunosuppressants and other main. 1. Physiological: hematuria and proteinuria may occur at the same time after strenuous exercise, and may return to normal after rest, usually do not worry too much. 2. Pathologic: including acute and chronic nephritis, nephrotic syndrome, lupus nephritis and other diseases. Acute nephritis treatment is based on bed rest, anti-infection and other symptomatic supportive treatment, and those with obvious edema can use furosemide and other diuretics appropriately. Acute and chronic nephritis, nephrotic syndrome treatment is based on ACEI or ARB drugs to lower blood pressure and protein, etc. Commonly used drugs include valsartan, chlorosartan, enalapril, captopril and so on. If the pathological type is clear, hormones and immunosuppressants can be given. Hormones include prednisone, methylprednisolone, etc. Immunosuppressants include cyclophosphamide, cyclosporine, etc. Lupus nephritis belongs to the category of chronic kidney disease, based on the principle of integrated treatment, hormones, immunosuppressants, etc. are used according to the situation. All of the above drugs need to be used under the guidance of a doctor. Urine protein, urine occult blood are 3 + may also have other reasons, the patient should go to the hospital in time, under the guidance of a professional physician treatment, do not self-medication.