In February, the Department of Cardiology was the first in China to successfully perform interventional treatment for an 81-year-old patient with a perivalvular leak after aortic valve replacement. The patient had undergone aortic valve replacement 8 years ago and still had recurrent postoperative symptoms of cardiac insufficiency. In recent January, the patient’s symptoms worsened and he developed nocturnal dyspnea. The patient was referred to the Department of Cardiology for minimally invasive interventional treatment because of his advanced age and the high surgical risks associated with traditional open-heart prosthetic valve replacement or valve repair. After aggressive preoperative preparation, Dr. Xin Pan, deputy chief of the Department of Cardiology, performed the procedure. Under local anesthesia in the catheterization laboratory, only one femoral artery was punctured, and the appropriately shaped and sized blocker material was accurately delivered to the perivalvular leak site through a very thin delivery catheter. The postoperative ultrasound showed that the aortic regurgitation basically disappeared and did not affect the normal opening and closing of the mechanical valve, and the patient was discharged one week later with significant improvement in cardiac insufficiency symptoms. Valvular heart disease still has a high incidence in China, and the vast majority of valve diseases require open-heart surgery for valve replacement until the advanced stage of the disease, and with the increase in the number of surgical valve replacement cases, the number of patients with perivalvular leaks is gradually increasing. It is generally accepted that perivalvular leaks occur because of surgical damage to the annulus, especially in the elderly combined with valve and annular calcification, resulting in poor healing of the annulus and suture ring. This is followed by inflammation causing suture tears. Perivalvular leakage is a common complication after prosthetic heart valve replacement, with an incidence of approximately 2% to 15%. Patients with significant perivalvular regurgitation due to perivalvular leak may exhibit weakness, dizziness, and fever, with a characteristic murmur in the corresponding auscultatory area. Some patients may also present with hemolytic anemia and cardiac insufficiency. These clinical symptoms may appear immediately after the procedure or several years after the procedure. The successful sealing of perivalvular leaks after aortic mechanical valve replacement in our cardiology department suggests that with the development of interventional materials and improved interventional techniques, it is feasible to treat perivalvular leaks without surgery, and will provide a minimally invasive treatment option for most patients with perivalvular leaks, as well as provide a better opportunity for It will provide a minimally invasive treatment option for the majority of patients with perivalvular leaks, and will also provide cardiac surgeons with a better chance to perform valve surgery.