Thighs appear red blood vessels mesh lines may be related to obesity lines, adverse reactions to topical drugs, Cushing’s syndrome and other reasons. 1. Obesity lines: due to the rapid increase in the volume of bone and muscle over the skin extension rate, which can lead to dermal elastic fibers are pulled off the formation. 2. Adverse reactions to topical drugs: such as thighs with eczema dermatitis, long-term use of glucocorticoid creams and lead to adverse reactions such as thinning of the skin, capillary dilatation, etc., can also cause the thighs appear red vascular grid-like lines. 3. Cushing’s syndrome: patients with increased concentrations of cortisol in the blood can cause capillary dilation of the thighs, appearing red vascular mesh-like lines. It is recommended that people with red vascular mesh-like lines on the thighs go to a regular hospital in time to clarify the cause, and if treatment is needed, standardized treatment should be carried out under the guidance of a doctor.